CACANA1A mutations causing episodic and progressive ataxia alter channel trafficking and kinetics

Keyphrases

• Episodic Ataxia 100%
• Ion Channel Kinetics 100%
• Progressive Ataxia 100%
• Plasma Membrane Targeting 100%
• Channel Trafficking 100%
• Cav2.1 100%
• Protein Trafficking 100%
• CACNA1C 100%
• Cerebellar Degeneration 50%
• Cerebellar Ataxia 50%
• Two-pore 50%
• Protein Folding 50%
• Protein Misfolding 50%
• P/Q-type Voltage-gated Calcium Channels 50%
• Protein Aggregation 50%
• Slowly Progressive 50%
• Neurological Disturbances 50%
• Neuronal Injury 50%
• Pore-forming Subunit 50%

Biochemistry, Genetics and Molecular Biology

• Protein Targeting 100%
• Cav2.1 100%
• Protein Aggregation 50%
• Protein Folding 50%
• Protein Misfolding 50%
• Voltage Gated Calcium Channel 50%

Neuroscience

• Missense Mutation 66%
• Protein Targeting 66%
• Membrane Targeting 66%
• Cav2.1 66%
• Protein Folding 33%
• Protein Aggregation 33%
• Protein Misfolding 33%