Bypassing the blues: Insomnia in the depressed post-CABG population

Lauren A. Waterman, Bea Herbeck Belnap, Marie Anne Gebara, Yan Huang, Kaleab Z. Abebe, Bruce L. Rollman, Jordan F. Karp

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


background: Recovery from coronary artery bypass graft (CABG) surgery often is complicated by depression and insomnia, resulting in poorer health-related quality of life and clinical outcomes. We explored the relationships among depression, insomnia, quality of life, and the impact of a collaborative care strategy on reducing insomnia in patients after CABG surgery. methods: Patients with a Patient Health Questionnaire score >10 were randomized to nurse-delivered collaborative care for depression (n = 150) or their physician's usual care (n = 152). A convenience sample of patients without depression (n = 151) served as the control group. Using the Hamilton Depression Rating Scale sleep questions, we created an "insomnia index." results: At baseline, 63% of participants who were depressed vs 12% of those who were not depressed reported insomnia. Compared with usual care, fewer collaborative care participants reported insomnia at 8 months, and they tended to have a lower insomnia score (insomnia index change score-0.95 and-1.47, respectively; P = .05) with no time-by-randomization interaction, Cohen's d = 0.22 (95% confidence interval,-0.001 to 0.43). Participants with baseline insomnia reported greater improvements in mental health-related quality of life (Medical Outcomes Survey 36-item Short Form Mental Component Summary score;-3.32, P = .02), but insomnia was not a significant moderator of the effect of collaborative care.

Original languageEnglish (US)
Pages (from-to)17-26
Number of pages10
JournalAnnals of Clinical Psychiatry
Issue number1
StatePublished - Feb 2020
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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