Bronchoalveolar lavage as a research tool

Anthony S. Rose; Kenneth S. Knox

doi:10.1055/s-2007-991528

Bronchoalveolar lavage as a research tool

Anthony S. Rose, Kenneth S. Knox

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Researchers over the past 40 years have utilized bronchoalveolar lavage (BAL) as a tool to help expand our knowledge of pulmonary medicine. Many reports have documented BAL as a safe procedure for research subjects. New technologies, such as flow cytometry, have provided much needed insight into the mechanisms behind several pulmonary diseases. The concept of the lung as an easily accessible mucosal site to monitor local immune responses and treatment effects is evolving. Future BAL research with human subjects, aided by new technology, will undoubtedly yield clinically relevant information regarding biomarkers of disease and new therapeutic targets.

Original language	English (US)
Pages (from-to)	561-573
Number of pages	13
Journal	Seminars in Respiratory and Critical Care Medicine
Volume	28
Issue number	5
DOIs	https://doi.org/10.1055/s-2007-991528
State	Published - Oct 2007
Externally published	Yes

Keywords

Acellular
Bronchoalveolar lavage fluid
Cytometry
Immunology
Safety

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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AB - Researchers over the past 40 years have utilized bronchoalveolar lavage (BAL) as a tool to help expand our knowledge of pulmonary medicine. Many reports have documented BAL as a safe procedure for research subjects. New technologies, such as flow cytometry, have provided much needed insight into the mechanisms behind several pulmonary diseases. The concept of the lung as an easily accessible mucosal site to monitor local immune responses and treatment effects is evolving. Future BAL research with human subjects, aided by new technology, will undoubtedly yield clinically relevant information regarding biomarkers of disease and new therapeutic targets.

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KW - Bronchoalveolar lavage fluid

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KW - Immunology

KW - Safety

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Bronchoalveolar lavage as a research tool

Abstract

Keywords

ASJC Scopus subject areas

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