Brain functional imaging using time-of-flight optical spectroscopy

Susan R. Hintz; David A. Benaron; Robert Robbins; Joshua L. Duckworth; Aileen L. Murphy; John W. Price; Frank W.H. Liu; David K. Stevenson; Wai Fung Cheong

doi:10.1117/12.301050

Brain functional imaging using time-of-flight optical spectroscopy

Susan R. Hintz, David A. Benaron, Robert Robbins, Joshua L. Duckworth, Aileen L. Murphy, John W. Price, Frank W.H. Liu, David K. Stevenson, Wai Fung Cheong

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

We measured the changes in oxygenation of the brain in animals and humans during changes in oxygen delivery (hypotension, shock) or during brain activation (such as finger movement). We found that such changes were measurable. In addition, we found that we were able to detect a change in the oxygenation signal in an animal undergoing heart surgery before the problem was clinically noted, thus suggesting that such methods may allow for earlier intervention in the intensive care setting.

Original language	English (US)
Pages (from-to)	176-183
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3194
DOIs	https://doi.org/10.1117/12.301050
State	Published - 1997
Externally published	Yes
Event	Proceedings of Photon Propagation in Tissues III - San Remo, Italy Duration: Sep 6 1997 → Sep 8 1997

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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title = "Brain functional imaging using time-of-flight optical spectroscopy",

abstract = "We measured the changes in oxygenation of the brain in animals and humans during changes in oxygen delivery (hypotension, shock) or during brain activation (such as finger movement). We found that such changes were measurable. In addition, we found that we were able to detect a change in the oxygenation signal in an animal undergoing heart surgery before the problem was clinically noted, thus suggesting that such methods may allow for earlier intervention in the intensive care setting.",

author = "Hintz, {Susan R.} and Benaron, {David A.} and Robert Robbins and Duckworth, {Joshua L.} and Murphy, {Aileen L.} and Price, {John W.} and Liu, {Frank W.H.} and Stevenson, {David K.} and Cheong, {Wai Fung}",

year = "1997",

doi = "10.1117/12.301050",

language = "English (US)",

volume = "3194",

pages = "176--183",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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note = "Proceedings of Photon Propagation in Tissues III ; Conference date: 06-09-1997 Through 08-09-1997",

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TY - JOUR

T1 - Brain functional imaging using time-of-flight optical spectroscopy

AU - Hintz, Susan R.

AU - Benaron, David A.

AU - Robbins, Robert

AU - Duckworth, Joshua L.

AU - Murphy, Aileen L.

AU - Price, John W.

AU - Liu, Frank W.H.

AU - Stevenson, David K.

AU - Cheong, Wai Fung

PY - 1997

Y1 - 1997

N2 - We measured the changes in oxygenation of the brain in animals and humans during changes in oxygen delivery (hypotension, shock) or during brain activation (such as finger movement). We found that such changes were measurable. In addition, we found that we were able to detect a change in the oxygenation signal in an animal undergoing heart surgery before the problem was clinically noted, thus suggesting that such methods may allow for earlier intervention in the intensive care setting.

AB - We measured the changes in oxygenation of the brain in animals and humans during changes in oxygen delivery (hypotension, shock) or during brain activation (such as finger movement). We found that such changes were measurable. In addition, we found that we were able to detect a change in the oxygenation signal in an animal undergoing heart surgery before the problem was clinically noted, thus suggesting that such methods may allow for earlier intervention in the intensive care setting.

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U2 - 10.1117/12.301050

DO - 10.1117/12.301050

M3 - Conference article

AN - SCOPUS:0031289527

SN - 0277-786X

VL - 3194

SP - 176

EP - 183

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Proceedings of Photon Propagation in Tissues III

Y2 - 6 September 1997 through 8 September 1997

ER -

Brain functional imaging using time-of-flight optical spectroscopy

Abstract

ASJC Scopus subject areas

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