Brain functional imaging using time-of-flight optical spectroscopy

Susan R. Hintz, David A. Benaron, Robert Robbins, Joshua L. Duckworth, Aileen L. Murphy, John W. Price, Frank W.H. Liu, David K. Stevenson, Wai Fung Cheong

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


We measured the changes in oxygenation of the brain in animals and humans during changes in oxygen delivery (hypotension, shock) or during brain activation (such as finger movement). We found that such changes were measurable. In addition, we found that we were able to detect a change in the oxygenation signal in an animal undergoing heart surgery before the problem was clinically noted, thus suggesting that such methods may allow for earlier intervention in the intensive care setting.

Original languageEnglish (US)
Pages (from-to)176-183
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 1997
Externally publishedYes
EventProceedings of Photon Propagation in Tissues III - San Remo, Italy
Duration: Sep 6 1997Sep 8 1997

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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