Bone mineral and predictors of bone mass in white, Hispanic, and Asian early pubertal girls

C. M. Weaver, L. D. McCabe, G. P. McCabe, R. Novotny, M. Van Loan, S. Going, V. Matkovic, C. Boushey, D. A. Savaiano

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Differences in bone among racial/ethnic groups may be explained by differences in body size and shape. Previous studies have not completely explained differences among white, Asian, and Hispanic groups during growth. To determine racial/ethnic differences and predictors of bone mass in early pubertal girls, we measured bone mineral content (BMC) in white, Hispanic, and Asian sixth-grade girls across six states in the United States. We developed models for predicting BMC for the total-body, distal radius, total-hip, and lumbar spine for 748 subjects. For each of the bone sites, the corresponding area from dual-energy X-ray absorptiometry (DXA) was a strong predictor of BMC, with correlations ranging 0.78-0.98, confirming that larger subjects have more BMC. Anthropometric measures of bone area were nearly as effective as bone area from DXA at predicting BMC. For total-body, distal radius, lumbar spine, and total-hip BMC, racial/ethnic differences were explained by differences in bone area, sexual maturity, physical activity, and dairy calcium intake. Bone size explained most of the racial/ethnic differences in BMC, although behavioral indicators were also significant predictors of BMC.

Original languageEnglish (US)
Pages (from-to)352-363
Number of pages12
JournalCalcified Tissue International
Issue number5
StatePublished - Nov 2007


  • Anthropometry
  • Bone
  • Ethnicity
  • Girls
  • Puberty
  • Race

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine
  • Endocrinology


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