Blood groups in two Amish demes

V. A. McKusick; W. B. Bias; R. A. Norum; H. E. Cross

doi:10.1007/BF00286209

Blood groups in two Amish demes

V. A. McKusick, W. B. Bias, R. A. Norum, H. E. Cross

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Blood group studies in two Old Order Amish isolates support previous evidence for genetic differences in the two groups. The more completely studied Amish community, that of Lancaster Co., Pa., revealed higher A and lower O phenotype frequencies than found in the Amish of Holmes Co., Ohio. In both groups, about one-fourth of individuals are Rh negative. Three blood group genes (Kell-positive, CD^ue and CDE) are present in low frequency in the Lancaster Amish, and pedigree studies identified individuals who may have introduced them to the Amish. Preliminary studies of an unusual antibody found in one Amish female provide evidence for a "new" red cell antigen which is present in about one-fourth of Americans.

Original language	English (US)
Pages (from-to)	36-41
Number of pages	6
Journal	Human Genetics
Volume	5
Issue number	1
DOIs	https://doi.org/10.1007/BF00286209
State	Published - Mar 1967
Externally published	Yes

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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abstract = "Blood group studies in two Old Order Amish isolates support previous evidence for genetic differences in the two groups. The more completely studied Amish community, that of Lancaster Co., Pa., revealed higher A and lower O phenotype frequencies than found in the Amish of Holmes Co., Ohio. In both groups, about one-fourth of individuals are Rh negative. Three blood group genes (Kell-positive, CDue and CDE) are present in low frequency in the Lancaster Amish, and pedigree studies identified individuals who may have introduced them to the Amish. Preliminary studies of an unusual antibody found in one Amish female provide evidence for a {"}new{"} red cell antigen which is present in about one-fourth of Americans.",

author = "McKusick, {V. A.} and Bias, {W. B.} and Norum, {R. A.} and Cross, {H. E.}",

year = "1967",

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AU - McKusick, V. A.

AU - Bias, W. B.

AU - Norum, R. A.

AU - Cross, H. E.

PY - 1967/3

Y1 - 1967/3

N2 - Blood group studies in two Old Order Amish isolates support previous evidence for genetic differences in the two groups. The more completely studied Amish community, that of Lancaster Co., Pa., revealed higher A and lower O phenotype frequencies than found in the Amish of Holmes Co., Ohio. In both groups, about one-fourth of individuals are Rh negative. Three blood group genes (Kell-positive, CDue and CDE) are present in low frequency in the Lancaster Amish, and pedigree studies identified individuals who may have introduced them to the Amish. Preliminary studies of an unusual antibody found in one Amish female provide evidence for a "new" red cell antigen which is present in about one-fourth of Americans.

AB - Blood group studies in two Old Order Amish isolates support previous evidence for genetic differences in the two groups. The more completely studied Amish community, that of Lancaster Co., Pa., revealed higher A and lower O phenotype frequencies than found in the Amish of Holmes Co., Ohio. In both groups, about one-fourth of individuals are Rh negative. Three blood group genes (Kell-positive, CDue and CDE) are present in low frequency in the Lancaster Amish, and pedigree studies identified individuals who may have introduced them to the Amish. Preliminary studies of an unusual antibody found in one Amish female provide evidence for a "new" red cell antigen which is present in about one-fourth of Americans.

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Blood groups in two Amish demes

Abstract

ASJC Scopus subject areas

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