Abstract
The use of a field-deployable biosensor device in a networked system in a real animal/human environment is important to monitor the spread of dangerous viral pathogens. Surrogate molecules have been used to perform experimental monitoring and/or computational fluid dynamics (CFD) studies, including smoke (for particulate movement) and CO2 (to simulate respiration). The current standard for detecting both porcine reproductive and respiratory syndrome (PRRSV) and influenza A is reverse transcription polymerase chain reaction (RT-PCR), which may take up to four hours to perform, including sample pre-processing, reverse transcription, thermocycling, and gel imaging for product identification. A lab-on-a-chip (LOC) is used to monitor airborne pathogens and enable to perform sample handling, mixing, dilution, electrophoresis, staining, and detection in a single integrated system. The three-dimensional CFD model would serve as a good model for monitoring the spread of many other viral pathogens within animal and human environments.
Original language | English (US) |
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Pages (from-to) | 5-7 |
Number of pages | 3 |
Journal | Resource: Engineering and Technology for Sustainable World |
Volume | 17 |
Issue number | 5 |
State | Published - Sep 2010 |
ASJC Scopus subject areas
- Biotechnology
- General Agricultural and Biological Sciences
- General Engineering