Bioprosthetic aortic paravalvular leak: Is valve-in-valve another solution?

Anwar Tandar, David A. Bull, Frederick G.P. Welt

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Paravalvular leak (PVL) following aortic valve implantation is a rare complication but may cause potentially serious consequences. It occurs in 2%-10% of surgical aortic valve replacements and 7%-17% of surgical mitral valve replacements. Transcatheter valve replacement data show that significant PVL occurs in 6%-8% of cases. The management of significant PVL has traditionally involved repeat surgical repair. However, many of these patients are considered too high risk to undergo a repeat surgical procedure; hence, a percutaneous transcatheter approach has often been utilized to treat these patients. Vascular plugs have been used to close PVLs, with variable results; the procedure is complex and technically demanding. Transcatheter aortic valve replacement, using a valve-in-valve approach, may provide an alternative approach for bioprosthetic PVL in the aortic position.

Original languageEnglish (US)
Pages (from-to)E1-E7
JournalJournal of Invasive Cardiology
Issue number1
StatePublished - Jan 2017
Externally publishedYes


  • paravalvular leak
  • vascular plugs

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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