Biomechanical models of hyphal growth in actinomycetes

Alain Goriely; Michael Tabor

doi:10.1016/S0022-5193(03)00029-8

Biomechanical models of hyphal growth in actinomycetes

Alain Goriely
, Michael Tabor

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

The tip growth of filamentary actinomycetes is investigated within the framework of large deformation membrane theory in which the cell wall is represented as a growing elastic membrane with geometry-dependent elastic properties. The model exhibits realistic hyphal shapes and indicates a self-similar tip growth mechanism consistent with that observed in experiments. It also demonstrates a simple mechanism for hyphal swelling and beading that is observed in the presence of a lysing agent.

Original language	English (US)
Pages (from-to)	211-218
Number of pages	8
Journal	Journal of Theoretical Biology
Volume	222
Issue number	2
DOIs	https://doi.org/10.1016/S0022-5193(03)00029-8
State	Published - May 21 2003

Keywords

Bio-elasticity
Filamentary micro-organisms
Large deformation theory
Tip growth

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Agricultural and Biological Sciences
Applied Mathematics

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10.1016/S0022-5193(03)00029-8

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title = "Biomechanical models of hyphal growth in actinomycetes",

abstract = "The tip growth of filamentary actinomycetes is investigated within the framework of large deformation membrane theory in which the cell wall is represented as a growing elastic membrane with geometry-dependent elastic properties. The model exhibits realistic hyphal shapes and indicates a self-similar tip growth mechanism consistent with that observed in experiments. It also demonstrates a simple mechanism for hyphal swelling and beading that is observed in the presence of a lysing agent.",

keywords = "Bio-elasticity, Filamentary micro-organisms, Large deformation theory, Tip growth",

author = "Alain Goriely and Michael Tabor",

note = "Funding Information: The authors wish to thank Liz Wellington (University of Warwick) for introducing them to this problem and for supplying a variety of bacterial samples; and David Bentley (Imaging Facility, Arizona Research Laboratories, University of Arizona) for his considerable help in imaging hyphal growth data. A. G. is supported by the Sloan Foundation and a Faculty Small Grant from the University of Arizona. M.T. was partially supported by National Science Foundation Grant DMS-9704421. ",

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AU - Tabor, Michael

N1 - Funding Information: The authors wish to thank Liz Wellington (University of Warwick) for introducing them to this problem and for supplying a variety of bacterial samples; and David Bentley (Imaging Facility, Arizona Research Laboratories, University of Arizona) for his considerable help in imaging hyphal growth data. A. G. is supported by the Sloan Foundation and a Faculty Small Grant from the University of Arizona. M.T. was partially supported by National Science Foundation Grant DMS-9704421.

PY - 2003/5/21

Y1 - 2003/5/21

N2 - The tip growth of filamentary actinomycetes is investigated within the framework of large deformation membrane theory in which the cell wall is represented as a growing elastic membrane with geometry-dependent elastic properties. The model exhibits realistic hyphal shapes and indicates a self-similar tip growth mechanism consistent with that observed in experiments. It also demonstrates a simple mechanism for hyphal swelling and beading that is observed in the presence of a lysing agent.

AB - The tip growth of filamentary actinomycetes is investigated within the framework of large deformation membrane theory in which the cell wall is represented as a growing elastic membrane with geometry-dependent elastic properties. The model exhibits realistic hyphal shapes and indicates a self-similar tip growth mechanism consistent with that observed in experiments. It also demonstrates a simple mechanism for hyphal swelling and beading that is observed in the presence of a lysing agent.

KW - Bio-elasticity

KW - Filamentary micro-organisms

KW - Large deformation theory

KW - Tip growth

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Biomechanical models of hyphal growth in actinomycetes

Abstract

Keywords

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