Biomarkers of cancer metastasis through the lymphovascular system: Future perspectives

Stanley P.L. Leong, Marlys Witte

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Cancer progression from the primary site to the regional lymph nodes and beyond to the distant sites through the lymphovascular system is genetically determined. In general, sentinel lymph node in the regional lymph nodes is the gateway for metastasis. Biomarkers are becoming increasingly important to define different phases of metastasis. With further understanding of the molecular mechanisms of metastasis, more targets are available for selective therapeutic intervention so that effective therapy can be delivered against cancer in a more personalized approach.

Original languageEnglish (US)
Pages (from-to)861-864
Number of pages4
JournalClinical and Experimental Metastasis
Issue number7
StatePublished - Oct 2012


  • Biomarkers
  • Cancer metastasis
  • Lymphovascular system

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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