Biomarkers of cancer metastasis through the lymphovascular system: Future perspectives

Stanley P.L. Leong; Marlys Witte

doi:10.1007/s10585-012-9522-0

Biomarkers of cancer metastasis through the lymphovascular system: Future perspectives

Stanley P.L. Leong, Marlys Witte

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Cancer progression from the primary site to the regional lymph nodes and beyond to the distant sites through the lymphovascular system is genetically determined. In general, sentinel lymph node in the regional lymph nodes is the gateway for metastasis. Biomarkers are becoming increasingly important to define different phases of metastasis. With further understanding of the molecular mechanisms of metastasis, more targets are available for selective therapeutic intervention so that effective therapy can be delivered against cancer in a more personalized approach.

Original language	English (US)
Pages (from-to)	861-864
Number of pages	4
Journal	Clinical and Experimental Metastasis
Volume	29
Issue number	7
DOIs	https://doi.org/10.1007/s10585-012-9522-0
State	Published - Oct 2012

Keywords

Biomarkers
Cancer metastasis
Lymphovascular system

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1007/s10585-012-9522-0

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abstract = "Cancer progression from the primary site to the regional lymph nodes and beyond to the distant sites through the lymphovascular system is genetically determined. In general, sentinel lymph node in the regional lymph nodes is the gateway for metastasis. Biomarkers are becoming increasingly important to define different phases of metastasis. With further understanding of the molecular mechanisms of metastasis, more targets are available for selective therapeutic intervention so that effective therapy can be delivered against cancer in a more personalized approach.",

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AB - Cancer progression from the primary site to the regional lymph nodes and beyond to the distant sites through the lymphovascular system is genetically determined. In general, sentinel lymph node in the regional lymph nodes is the gateway for metastasis. Biomarkers are becoming increasingly important to define different phases of metastasis. With further understanding of the molecular mechanisms of metastasis, more targets are available for selective therapeutic intervention so that effective therapy can be delivered against cancer in a more personalized approach.

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Biomarkers of cancer metastasis through the lymphovascular system: Future perspectives

Abstract

Keywords

ASJC Scopus subject areas

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