@inproceedings{11fdce49c12c4db990df7ffafd3d703e,
title = "Biocompatible electrospun titania-composite nanofiber networks for whole cell sensing",
abstract = "Biosensor technology includes the detection of generated biological functionality. One whole-cell biosensor concept leaves specific receptor molecules in their natural environment to be optimized and adapted for efficient molecular recognition during evolution, and to use intact cells as biologically-active elements. In this project, a basic nanomaterials platform for whole cell sensors is produced by electrospinning composite nano- and microfiber networks. The resulting polymer-metal oxide (titania) {"}nano-mats{"} are fabricated on a conductive indium tin oxide (ITO) coated glass substrate for epithelial or other cell incubation and future incorporation into bioelectronics. Impedance spectroscopy is used to characterize cell interactions with the nano-mat to detect changes in cells with proliferation or when exposed to chemical stimuli, such as lactic acid. Cell response to media conditions can include growth, attachment and s preading, motility and migration, and cell death.",
keywords = "Biosensor, Electrospinning, Impedance spectroscopy, Indium tin oxide, Titania nanofibers, Whole-cell sensing",
author = "Jabal, {Jamie M.F.} and Anjil Giri and Gustin, {Kurt E.} and Aston, {D. Eric}",
year = "2008",
language = "English (US)",
isbn = "0930815866",
series = "Proceedings - 2008 International Symposium on Microelectronics, IMAPS 2008",
pages = "827--833",
booktitle = "Proceedings - 2008 International Symposium on Microelectronics, IMAPS 2008",
note = "41st Annual International Symposium on Microelectronics, IMAPS 2008 ; Conference date: 02-11-2008 Through 06-11-2008",
}