Bio-soft matter imaging and micro-metrology by Phase-sensitive ultrasonic microscopy

W. Ngwa, W. Grill, T. Kundu

Research output: Contribution to journalConference articlepeer-review

5 Scopus citations


Phase-sensitive acoustic microscopy (PSAM) is used for investigating bio-soft matter systems constituting the important biopolymer and biomaterial chitosan. Incipient micro-analytic ways for the determination of mechanical properties from the simultaneously obtained amplitude and phase images, allow the coeval estimation of the depth of structures and acoustic velocities, from which the density, stiffness and other elastic parameters may be derived. Chitosan is an important derivative from chitin the major component of the carapace (also examined here) of living species like Daphnia. The results obtained exemplify the unique power of PSAM for revealing essential features and information in biological soft matter.

Original languageEnglish (US)
Pages (from-to)263-272
Number of pages10
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 2004
EventHealth Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems III - San Diego, CA, United States
Duration: Mar 15 2004Mar 17 2004


  • Acoustic impedance
  • Acoustic microscopy
  • Bio-soft matter
  • Carapace
  • Chitosan
  • Mechanical properties
  • P-wave speed
  • Phase-sensitive acoustic microscopy
  • Soft matter

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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