TY - JOUR
T1 - Big Data, Big Opportunities, and Big Challenges
AU - Frelinger, Jeffrey A.
N1 - Funding Information:
Funding for the Summit and the publication of this supplement was provided by the National Alopecia Areata Foundation and was made possible (in part) by a grant (R13AR067088-01) from the National Institute of Arthritis and Musculoskeletal and Skin Diseases and all co-funding support was provided by the National Center for Advancing Translational Sciences.
Funding Information:
JAF owns Amgen stock, has received grant support from the NIH, has received royalties from the sale of monoclonal antibodies through the University of Southern California.
Publisher Copyright:
© 2015 The Society for Investigative Dermatology.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - High-throughput assays have begun to revolutionize modern biology and medicine. The advent of cheap next-generation sequencing (NGS) has made it possible to interrogate cells and human populations as never before. Although this has allowed us to investigate the genetics, gene expression, and impacts of the microbiome, there remain both practical and conceptual challenges. These include data handling, storage, and statistical analysis, as well as an inherent problem of the analysis of heterogeneous cell populations.
AB - High-throughput assays have begun to revolutionize modern biology and medicine. The advent of cheap next-generation sequencing (NGS) has made it possible to interrogate cells and human populations as never before. Although this has allowed us to investigate the genetics, gene expression, and impacts of the microbiome, there remain both practical and conceptual challenges. These include data handling, storage, and statistical analysis, as well as an inherent problem of the analysis of heterogeneous cell populations.
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U2 - 10.1038/jidsymp.2015.38
DO - 10.1038/jidsymp.2015.38
M3 - Review article
C2 - 26551943
AN - SCOPUS:84946723555
SN - 1087-0024
VL - 17
SP - 33
EP - 35
JO - Journal of Investigative Dermatology Symposium Proceedings
JF - Journal of Investigative Dermatology Symposium Proceedings
IS - 2
ER -