Benign lesions mimicking malignant tumors of the esophagus

Barbara C. Wolf, Urmila Khettry, Howard K. Leonardi, Wilford B. Neptune, Achyut K. Bhattacharyya, Merle A. Legg

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Three cases of benign lesions which mimicked malignant tumors of the esophagus are described. In all three cases, two inflammatory pseudotumors and one case of diffuse leiomyomatosis, the clinical presentations, radiologic features, and gross pathologic findings led to the mistaken diagnosis of carcinoma at thoracotomy. The benign nature of the processes was recognizable only on microscopic examination. Although most benign tumors of the esophagus are localized solitary lesions that are easily distinguished from carcinoma, occasionally benign conditions may present as infiltrative, ulcerated mass lesions. Inflammatory pseudotumor and diffuse leiomyomatosis should be included in the differential diagnosis of esophageal malignancies.

Original languageEnglish (US)
Pages (from-to)148-154
Number of pages7
JournalHuman pathology
Issue number2
StatePublished - Feb 1988


  • benign lesions
  • differential diagnosis
  • eosphageal masses
  • inflammatory pseudotumor
  • leiomyomatosis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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