Beclomethasone dipropionate (BDP) is a long-acting inhaled corticosteroid, used for the treatment of asthma, and as an inhalation therapy with HFA-134a. The sample studied by X-ray crystallography was grown in a mixture of the aerosol propellant HFA-134a, C2H2F4, and 200-proof ethanol. The formula of the crystalline material is C 28H37ClO7·2C2H 6O·C2H2F4. In the crystal structure, disordered solvent occupies a channel which is perpendicular to the BDP molecules. The latter are are stacked together by hydrogen bonding.
|Original language||English (US)|
|Journal||Acta Crystallographica Section E: Structure Reports Online|
|State||Published - Nov 2003|
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics