Bayesian accelerated failure time analysis with application to veterinary epidemiology

Edward J. Bedrick, Ronald Christensen, Wesley O. Johnson

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Standard methods for analysing survival data with covariates rely on asymptotic inferences. Bayesian methods can be performed using simple computations and are applicable for any sample size. We propose a practical method for making prior specifications and discuss a complete Bayesian analysis for parametric accelerated failure time regression models. We emphasize inferences for the survival curve rather than regression coefficients. A key feature of the Bayesian framework is that model comparisons for various choices of baseline distribution are easily handled by the calculation of Bayes factors. Such comparisons between non-nested models are difficult in the frequentist setting. We illustrate diagnostic tools and examine the sensitivity of the Bayesian methods.

Original languageEnglish (US)
Pages (from-to)221-237
Number of pages17
JournalStatistics in Medicine
Volume19
Issue number2
DOIs
StatePublished - Jan 30 2000
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Statistics and Probability

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