Abstract
Introduction: Lung cancer patients presenting with advanced cancer face low survival rates and a high symptom burden. There have been mixed findings for the association between survival and various patient reported outcomes (PROs). Methods: We used prospective data from 111 lung cancer patients with advanced stage III/IV disease to investigate the association of survival with PROs (European Organization for Research and Treatment of Cancer Core-30 and Lung Module). Cox proportional hazard models were used to examine the individual association between several PRO measures and survival. Results: Pain in chest and global quality of life (QoL) were found to have the strongest association with survival with a 20% increased hazard of death per 10% increase in pain in chest and 14% decrease in hazard of death per 10% increase in global QoL. Conclusion: Our results provide more evidence for the value of PRO data to inform clinical and patient decision-making.
Original language | English (US) |
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Pages (from-to) | 635-641 |
Number of pages | 7 |
Journal | Journal of Psychosocial Oncology |
Volume | 38 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2 2020 |
Keywords
- Lung cancer
- oncology
- quality of life
- survival
- symptoms
ASJC Scopus subject areas
- Oncology
- Applied Psychology
- Psychiatry and Mental health