Baclofen overdose with cardiac conduction abnormalities: Case report and review of the literature

Sara Nugent; Michael D. Katz; Timothy E. Little

doi:10.3109/15563658608992596

Baclofen overdose with cardiac conduction abnormalities: Case report and review of the literature

Sara Nugent, Michael D. Katz, Timothy E. Little

Pharmacy Practice and Science

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Abstract

Cardiac conduction abnormalities and hypertension developed in a patient who ingested approximately 500 mg of baclofen (Lioresal^R). The patient also exhibited the more common features of baclofen overdose including coma, respiratory depression, hypotonia, and hyporeflexia. A review of the literature and a discussion of the interesting manifestations and treatment of baclofen overdose are included.

Original language	English (US)
Pages (from-to)	321-328
Number of pages	8
Journal	Clinical Toxicology
Volume	24
Issue number	4
DOIs	https://doi.org/10.3109/15563658608992596
State	Published - 1986

ASJC Scopus subject areas

Toxicology

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10.3109/15563658608992596

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title = "Baclofen overdose with cardiac conduction abnormalities: Case report and review of the literature",

abstract = "Cardiac conduction abnormalities and hypertension developed in a patient who ingested approximately 500 mg of baclofen (LioresalR). The patient also exhibited the more common features of baclofen overdose including coma, respiratory depression, hypotonia, and hyporeflexia. A review of the literature and a discussion of the interesting manifestations and treatment of baclofen overdose are included.",

author = "Sara Nugent and Katz, {Michael D.} and Little, {Timothy E.}",

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AB - Cardiac conduction abnormalities and hypertension developed in a patient who ingested approximately 500 mg of baclofen (LioresalR). The patient also exhibited the more common features of baclofen overdose including coma, respiratory depression, hypotonia, and hyporeflexia. A review of the literature and a discussion of the interesting manifestations and treatment of baclofen overdose are included.

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Baclofen overdose with cardiac conduction abnormalities: Case report and review of the literature

Abstract

ASJC Scopus subject areas

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