TY - GEN
T1 - Atomic resolution of cytoskeletal protein by scanning tunneling microscopy
AU - Hameroff, Stuart R.
AU - Vernetti, Lawrence A.
AU - Lee, Y. C.
AU - Sarid, Dror
AU - Watt, Richard C.
PY - 1990
Y1 - 1990
N2 - Preparation and scanning tunneling microscopy (STM) imaging of cytokeratin cytoskeletal protein are reported. Results show structures 45 nm in length, diameter 1.8 nm, with helical periodicity of 0.54 nm and a helical rise of 100 degrees. Atomic resolution as well as primary (individual amino acids), secondary (alpha helix), tertiary (dimer), and quaternary (tetramer) levels of protein structure are demonstrated. It is argued that STM may be used to modify, manipulate, and/or construct biomolecules and molecular devices.
AB - Preparation and scanning tunneling microscopy (STM) imaging of cytokeratin cytoskeletal protein are reported. Results show structures 45 nm in length, diameter 1.8 nm, with helical periodicity of 0.54 nm and a helical rise of 100 degrees. Atomic resolution as well as primary (individual amino acids), secondary (alpha helix), tertiary (dimer), and quaternary (tetramer) levels of protein structure are demonstrated. It is argued that STM may be used to modify, manipulate, and/or construct biomolecules and molecular devices.
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M3 - Conference contribution
AN - SCOPUS:0025532596
SN - 0879425598
T3 - Proceedings of the Annual Conference on Engineering in Medicine and Biology
SP - 1724
BT - Biomedical Engineering Perspectives
PB - Publ by IEEE
T2 - Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Y2 - 1 November 1990 through 4 November 1990
ER -