Asymmetric synthesis of (2R, 3S) and (2S, 3R) precursors of β-methyl-histidine, -phenylalanine and -tyrosine

Guigen Li; Dinesh Pattel; Victor J. Hruby

doi:10.1016/S0957-4166(00)80091-9

Asymmetric synthesis of (2R, 3S) and (2S, 3R) precursors of β-methyl-histidine, -phenylalanine and -tyrosine

Guigen Li
, Dinesh Pattel
, Victor J. Hruby

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

A systematic series of (2S, 3R) and (2R, 3S) precursors to β-methyl-histidine, -phenylalanine and -tyrosine, which are of significant importance in the design of peptide and protein ligands, have been synthesized in high optically purity and yield.

Original language	English (US)
Pages (from-to)	2315-2318
Number of pages	4
Journal	Tetrahedron: Asymmetry
Volume	4
Issue number	11
DOIs	https://doi.org/10.1016/S0957-4166(00)80091-9
State	Published - Nov 1993
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1016/S0957-4166(00)80091-9

Cite this

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title = "Asymmetric synthesis of (2R, 3S) and (2S, 3R) precursors of β-methyl-histidine, -phenylalanine and -tyrosine",

abstract = "A systematic series of (2S, 3R) and (2R, 3S) precursors to β-methyl-histidine, -phenylalanine and -tyrosine, which are of significant importance in the design of peptide and protein ligands, have been synthesized in high optically purity and yield.",

author = "Guigen Li and Dinesh Pattel and Hruby, \{Victor J.\}",

year = "1993",

month = nov,

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journal = "Tetrahedron: Asymmetry",

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AU - Li, Guigen

AU - Pattel, Dinesh

AU - Hruby, Victor J.

PY - 1993/11

Y1 - 1993/11

N2 - A systematic series of (2S, 3R) and (2R, 3S) precursors to β-methyl-histidine, -phenylalanine and -tyrosine, which are of significant importance in the design of peptide and protein ligands, have been synthesized in high optically purity and yield.

AB - A systematic series of (2S, 3R) and (2R, 3S) precursors to β-methyl-histidine, -phenylalanine and -tyrosine, which are of significant importance in the design of peptide and protein ligands, have been synthesized in high optically purity and yield.

UR - https://www.scopus.com/pages/publications/0027371781

UR - https://www.scopus.com/pages/publications/0027371781#tab=citedBy

U2 - 10.1016/S0957-4166(00)80091-9

DO - 10.1016/S0957-4166(00)80091-9

M3 - Article

AN - SCOPUS:0027371781

SN - 0957-4166

VL - 4

SP - 2315

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JO - Tetrahedron: Asymmetry

JF - Tetrahedron: Asymmetry

IS - 11

ER -

Asymmetric synthesis of (2R, 3S) and (2S, 3R) precursors of β-methyl-histidine, -phenylalanine and -tyrosine

Abstract

ASJC Scopus subject areas

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