TY - JOUR
T1 - Association between parity and obesity in Mexican and Mexican-American women
T2 - Findings from the ella binational breast cancer study
AU - Martínez, María Elena
AU - Pond, Erika
AU - Wertheim, Betsy C.
AU - Nodora, Jesse N.
AU - Jacobs, Elizabeth T.
AU - Bondy, Melissa
AU - Daneri-Navarro, Adrian
AU - Meza-Montenegro, Maria Mercedes
AU - Gutierrez-Millan, Luis Enrique
AU - Brewster, Abenaa
AU - Komenaka, Ian K.
AU - Thompson, Patricia
N1 - Funding Information:
Fang Wang for their contributions. Grant support: Avon Foundation, Arizona Cancer Center Core Grant from the National Cancer Institute (CA-023074-2953), M.D. Anderson Cancer Center Specialized Program of Research Excellence in Breast Cancer (P50 CA116199-02S1), and Susan G. Komen for the Cure®(KG090934).
PY - 2013/4
Y1 - 2013/4
N2 - Obesity at diagnosis of breast cancer is associated with higher all-cause mortality and treatment-associated toxicities. We evaluated the association between parity and obesity in the Ella study, a population of Mexican and Mexican-American breast cancer patients with high parity. Obesity outcomes included body mass index (BMI) ≥30 kg/m2, waist circumference (WC) ≥35 in (88 cm), and waist-to-hip-ratio (WHR) ≥0.85. Prevalence of obesity ([BMI] ≥ 30 kg/m2) was 38.9 %. For WC, the multivariate odds ratio (OR) (95 % confidence interval [CI]) for having WC ≥ 35 inches in women with ≥4 pregnancies relative to those with 1-2 pregnancies was 1.59 (1.01-2.47). Higher parity (≥4 pregnancies) was non-significantly associated with high BMI (OR = 1.10; 95 % CI 0.73-1.67). No positive association was observed for WHR. Our results suggest WC is independently associated with high parity in Hispanic women and may be an optimal target for post-partum weight loss interventions.
AB - Obesity at diagnosis of breast cancer is associated with higher all-cause mortality and treatment-associated toxicities. We evaluated the association between parity and obesity in the Ella study, a population of Mexican and Mexican-American breast cancer patients with high parity. Obesity outcomes included body mass index (BMI) ≥30 kg/m2, waist circumference (WC) ≥35 in (88 cm), and waist-to-hip-ratio (WHR) ≥0.85. Prevalence of obesity ([BMI] ≥ 30 kg/m2) was 38.9 %. For WC, the multivariate odds ratio (OR) (95 % confidence interval [CI]) for having WC ≥ 35 inches in women with ≥4 pregnancies relative to those with 1-2 pregnancies was 1.59 (1.01-2.47). Higher parity (≥4 pregnancies) was non-significantly associated with high BMI (OR = 1.10; 95 % CI 0.73-1.67). No positive association was observed for WHR. Our results suggest WC is independently associated with high parity in Hispanic women and may be an optimal target for post-partum weight loss interventions.
KW - Body mass index
KW - Hispanic women
KW - Obesity
KW - Parity
KW - Waist circumference
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U2 - 10.1007/s10903-012-9649-8
DO - 10.1007/s10903-012-9649-8
M3 - Article
C2 - 22618357
AN - SCOPUS:84882889603
SN - 1557-1912
VL - 15
SP - 234
EP - 243
JO - Journal of Immigrant and Minority Health
JF - Journal of Immigrant and Minority Health
IS - 2
ER -