Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Ali F. Jon; Ahmad R. Cheema; Atif N. Khan; Vassilios Raptopoulos; Thomas Hauser; Imad Nasser; Francine K. Welty; Andrew Karellas; Melvin E. Clouse

doi:10.1016/j.clinimag.2014.01.005

Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Ali F. Jon
, Ahmad R. Cheema
, Atif N. Khan
, Vassilios Raptopoulos
, Thomas Hauser
, Imad Nasser
, Francine K. Welty
, Andrew Karellas
, Melvin E. Clouse

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CT_FPI) compared to liver spleen method (CT_L/S, CT_L-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CT_FPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CT_FPI and the standard method of assessing liver fat using CT_L/S (r=-0.901), CT_L-S (r=-0.911). Hepatic HU and CT_FPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

Original language	English (US)
Pages (from-to)	259-264
Number of pages	6
Journal	Clinical Imaging
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/j.clinimag.2014.01.005
State	Published - May 2014
Externally published	Yes

Keywords

Fat percent index
Hepatic steatosis assessment
Metabolic syndrome
NASH
Noncontrast CT
Obesity

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2014.01.005

Cite this

@article{86df2f227c424cbaaa537635e46dc973,

title = "Assessment of liver fat in an obese patient population using noncontrast CT fat percent index",

abstract = "Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat \% index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.",

keywords = "Fat percent index, Hepatic steatosis assessment, Metabolic syndrome, NASH, Noncontrast CT, Obesity",

author = "Jon, \{Ali F.\} and Cheema, \{Ahmad R.\} and Khan, \{Atif N.\} and Vassilios Raptopoulos and Thomas Hauser and Imad Nasser and Welty, \{Francine K.\} and Andrew Karellas and Clouse, \{Melvin E.\}",

year = "2014",

month = may,

doi = "10.1016/j.clinimag.2014.01.005",

language = "English (US)",

volume = "38",

pages = "259--264",

journal = "Clinical Imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

AU - Jon, Ali F.

AU - Cheema, Ahmad R.

AU - Khan, Atif N.

AU - Raptopoulos, Vassilios

AU - Hauser, Thomas

AU - Nasser, Imad

AU - Welty, Francine K.

AU - Karellas, Andrew

AU - Clouse, Melvin E.

PY - 2014/5

Y1 - 2014/5

N2 - Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

AB - Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

KW - Fat percent index

KW - Hepatic steatosis assessment

KW - Metabolic syndrome

KW - NASH

KW - Noncontrast CT

KW - Obesity

UR - https://www.scopus.com/pages/publications/84899090793

UR - https://www.scopus.com/pages/publications/84899090793#tab=citedBy

U2 - 10.1016/j.clinimag.2014.01.005

DO - 10.1016/j.clinimag.2014.01.005

M3 - Article

C2 - 24559751

AN - SCOPUS:84899090793

SN - 0899-7071

VL - 38

SP - 259

EP - 264

JO - Clinical Imaging

JF - Clinical Imaging

IS - 3

ER -

Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Abstract

Keywords

ASJC Scopus subject areas

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