Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Ali F. Jon; Ahmad R. Cheema; Atif N. Khan; Vassilios Raptopoulos; Thomas Hauser; Imad Nasser; Francine K. Welty; Andrew Karellas; Melvin E. Clouse

doi:10.1016/j.clinimag.2014.01.005

Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Ali F. Jon, Ahmad R. Cheema, Atif N. Khan, Vassilios Raptopoulos, Thomas Hauser, Imad Nasser, Francine K. Welty, Andrew Karellas, Melvin E. Clouse

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CT_FPI) compared to liver spleen method (CT_L/S, CT_L-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CT_FPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CT_FPI and the standard method of assessing liver fat using CT_L/S (r=-0.901), CT_L-S (r=-0.911). Hepatic HU and CT_FPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

Original language	English (US)
Pages (from-to)	259-264
Number of pages	6
Journal	Clinical Imaging
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/j.clinimag.2014.01.005
State	Published - May 2014
Externally published	Yes

Keywords

Fat percent index
Hepatic steatosis assessment
Metabolic syndrome
NASH
Noncontrast CT
Obesity

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1016/j.clinimag.2014.01.005

Cite this

@article{86df2f227c424cbaaa537635e46dc973,

title = "Assessment of liver fat in an obese patient population using noncontrast CT fat percent index",

abstract = "Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.",

keywords = "Fat percent index, Hepatic steatosis assessment, Metabolic syndrome, NASH, Noncontrast CT, Obesity",

author = "Jon, {Ali F.} and Cheema, {Ahmad R.} and Khan, {Atif N.} and Vassilios Raptopoulos and Thomas Hauser and Imad Nasser and Welty, {Francine K.} and Andrew Karellas and Clouse, {Melvin E.}",

year = "2014",

month = may,

doi = "10.1016/j.clinimag.2014.01.005",

language = "English (US)",

volume = "38",

pages = "259--264",

journal = "Clinical Imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

AU - Jon, Ali F.

AU - Cheema, Ahmad R.

AU - Khan, Atif N.

AU - Raptopoulos, Vassilios

AU - Hauser, Thomas

AU - Nasser, Imad

AU - Welty, Francine K.

AU - Karellas, Andrew

AU - Clouse, Melvin E.

PY - 2014/5

Y1 - 2014/5

N2 - Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

AB - Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

KW - Fat percent index

KW - Hepatic steatosis assessment

KW - Metabolic syndrome

KW - NASH

KW - Noncontrast CT

KW - Obesity

UR - http://www.scopus.com/inward/record.url?scp=84899090793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899090793&partnerID=8YFLogxK

U2 - 10.1016/j.clinimag.2014.01.005

DO - 10.1016/j.clinimag.2014.01.005

M3 - Article

C2 - 24559751

AN - SCOPUS:84899090793

SN - 0899-7071

VL - 38

SP - 259

EP - 264

JO - Clinical Imaging

JF - Clinical Imaging

IS - 3

ER -

Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this