Assessment of dietary amino acid scarcity on growth and blood plasma proteome status of broiler chickens

A. Corzo, M. T. Kidd, M. D. Koter, S. C. Burgess

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Dietary Lys needs for chicks were studied. A titration diet consisting of progressive amounts of dietary Lys from 0.95% up to 1.40% was fed to broiler chicks from 0 to 18 d of age. Optimal dietary Lys level was calculated using regression analysis. Body weight gain and feed conversion were maximized at Lys levels of 1.24% (1.10% digestible) and 1.27% (1.13% digestible) of diet, respectively. Blood samples were then collected from 2 groups: birds fed the lowest Lys level and birds fed dietary Lys nearest the determined requirement level (1.25% Lys). Plasma was analyzed for protein spectra via mass spectrometry and then classified by their functional characteristics. The number of proteins was similar between the 2 samples, but there was a tendency toward increased peptides for specific proteins in plasma from chicks fed adequate Lys levels. Furthermore, after these proteins were classified, more muscle-related proteins were found in plasma samples of birds fed Lys-adequate diets. It would appear that an individual dietary amino acid deficiency does not necessarily translate into decreasing protein synthesis proportionate to body weight, but rather significant changes may be occurring within the types of proteins undergoing anabolism. In conclusion, results herein illustrate the potential for using functional genomics in nutritionally related responses of poultry.

Original languageEnglish (US)
Pages (from-to)419-425
Number of pages7
JournalPoultry science
Issue number3
StatePublished - Mar 2005


  • Broiler
  • Lysine
  • Mass spectrometry
  • Plasma
  • Proteomics

ASJC Scopus subject areas

  • Animal Science and Zoology


Dive into the research topics of 'Assessment of dietary amino acid scarcity on growth and blood plasma proteome status of broiler chickens'. Together they form a unique fingerprint.

Cite this