Assessing respiratory function in young children: Developmental considerations

Gary L. Larsen, June Ku Brian Kang, Theresa Guilbert, Wayne Morgan

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


The purpose of this review is to provide practitioners and clinical investigators with an update on methods of assessing respiratory function in young children. The importance of this topic is presented in light of the natural history of asthma, as well as maturational changes that occur early in life in terms of airway development. Models of disease are cited to support the concept that injury of the mammalian airway early in postnatal life might have far-reaching consequences in terms of control of airway caliber and responsiveness. The methods currently available to measure respiratory function in our younger patients are outlined. The ability of children to perform the maneuvers necessary for this testing is considered as a function of age. Areas in which research and development are needed are highlighted.

Original languageEnglish (US)
Pages (from-to)657-666
Number of pages10
JournalJournal of Allergy and Clinical Immunology
Issue number4
StatePublished - Apr 2005


  • Airway development
  • Childhood asthma
  • Forced oscillation techniques
  • Interrupter techniques
  • Pulmonary function tests
  • Spirometry
  • Whole body plethysmography

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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