Aspirin in Ischemic Heart Disease

Steven Goldman; Karen Zadina; Jack Copeland; Thomas Moritz; William Henderson; Masoor Kamalesh; Charles H. Hennekens; Julie E. Buring; Richard Peto; John E. Willard; Richard A. Lange; L. David Hillis

doi:10.1056/NEJM199211123272011

Aspirin in Ischemic Heart Disease

Steven Goldman, Karen Zadina, Jack Copeland, Thomas Moritz, William Henderson, Masoor Kamalesh, Charles H. Hennekens, Julie E. Buring, Richard Peto, John E. Willard, Richard A. Lange, L. David Hillis

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Abstract

To the Editor: In their excellent review article on the use of aspirin in ischemic heart disease (July 16 issue),¹ Willard et al. cite the Department of Veterans Affairs cooperative studies,² ^, ³ but we would like to emphasize that our recent work demonstrates that preoperative aspirin offers no additional benefit in early vein-graft patency as compared with aspirin therapy (325 mg) that begins six hours after surgery. Moreover, by avoiding preoperative aspirin, it is possible to eliminate potential bleeding complications.⁴ For completeness, we would also like to point out that although aspirin has been shown to improve vein-graft patency both one…

Original language	English (US)
Pages (from-to)	1455-1456
Number of pages	2
Journal	New England Journal of Medicine
Volume	327
Issue number	20
DOIs	https://doi.org/10.1056/NEJM199211123272011
State	Published - Nov 12 1992
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1056/NEJM199211123272011

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title = "Aspirin in Ischemic Heart Disease",

abstract = "To the Editor: In their excellent review article on the use of aspirin in ischemic heart disease (July 16 issue),1 Willard et al. cite the Department of Veterans Affairs cooperative studies,2 , 3 but we would like to emphasize that our recent work demonstrates that preoperative aspirin offers no additional benefit in early vein-graft patency as compared with aspirin therapy (325 mg) that begins six hours after surgery. Moreover, by avoiding preoperative aspirin, it is possible to eliminate potential bleeding complications.4 For completeness, we would also like to point out that although aspirin has been shown to improve vein-graft patency both one…",

author = "Steven Goldman and Karen Zadina and Jack Copeland and Thomas Moritz and William Henderson and Masoor Kamalesh and Hennekens, {Charles H.} and Buring, {Julie E.} and Richard Peto and Willard, {John E.} and Lange, {Richard A.} and Hillis, {L. David}",

year = "1992",

month = nov,

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doi = "10.1056/NEJM199211123272011",

language = "English (US)",

volume = "327",

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TY - JOUR

T1 - Aspirin in Ischemic Heart Disease

AU - Goldman, Steven

AU - Zadina, Karen

AU - Copeland, Jack

AU - Moritz, Thomas

AU - Henderson, William

AU - Kamalesh, Masoor

AU - Hennekens, Charles H.

AU - Buring, Julie E.

AU - Peto, Richard

AU - Willard, John E.

AU - Lange, Richard A.

AU - Hillis, L. David

PY - 1992/11/12

Y1 - 1992/11/12

N2 - To the Editor: In their excellent review article on the use of aspirin in ischemic heart disease (July 16 issue),1 Willard et al. cite the Department of Veterans Affairs cooperative studies,2 , 3 but we would like to emphasize that our recent work demonstrates that preoperative aspirin offers no additional benefit in early vein-graft patency as compared with aspirin therapy (325 mg) that begins six hours after surgery. Moreover, by avoiding preoperative aspirin, it is possible to eliminate potential bleeding complications.4 For completeness, we would also like to point out that although aspirin has been shown to improve vein-graft patency both one…

AB - To the Editor: In their excellent review article on the use of aspirin in ischemic heart disease (July 16 issue),1 Willard et al. cite the Department of Veterans Affairs cooperative studies,2 , 3 but we would like to emphasize that our recent work demonstrates that preoperative aspirin offers no additional benefit in early vein-graft patency as compared with aspirin therapy (325 mg) that begins six hours after surgery. Moreover, by avoiding preoperative aspirin, it is possible to eliminate potential bleeding complications.4 For completeness, we would also like to point out that although aspirin has been shown to improve vein-graft patency both one…

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M3 - Letter

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Aspirin in Ischemic Heart Disease

Abstract

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