Ascorbic acid absorption in man - pharmacokinetic implications

Michael Mayersohn

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Several early literature reports have suggested the possible existence of a non-passive, saturable process for ascorbic acid absorption in man. The recent work of several investigators confirms the existence of such a mechanism. Based upon an analysis of the data provided by these investigators values of Vmax and Km have been calculated using the equations of saturable absorption kinetics. A method of oral dosing is suggested which should maximize the total amount of vitamin absorbed.

Original languageEnglish (US)
Pages (from-to)140-142
Number of pages3
JournalEuropean Journal of Pharmacology
Issue number1
StatePublished - Jul 1972
Externally publishedYes


  • Ascorbic acid absorption
  • Saturable absorption

ASJC Scopus subject areas

  • Pharmacology


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