Several early literature reports have suggested the possible existence of a non-passive, saturable process for ascorbic acid absorption in man. The recent work of several investigators confirms the existence of such a mechanism. Based upon an analysis of the data provided by these investigators values of Vmax and Km have been calculated using the equations of saturable absorption kinetics. A method of oral dosing is suggested which should maximize the total amount of vitamin absorbed.
|Original language||English (US)|
|Number of pages||3|
|Journal||European Journal of Pharmacology|
|State||Published - Jul 1972|
- Ascorbic acid absorption
- Saturable absorption
ASJC Scopus subject areas