Arterial lipid characterization by high resolution TSI

Kang Kim, Russell Witte, M. O'Donnell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


High resolution Thermal Strain Imaging (TSI) using an ultrasound (US) microscope was applied to excised porcine tissues. Samples were placed in a temperature controlled water chamber and scanned transversely and longitudinally using a custom high resolution microscope. Phase-sensitive, correlation-based speckle tracking was applied to map the spatial distribution of temporal strain across the sample. TSI differentiated fatty tissue from the water-based arterial wall and muscle with high contrast and a spatial resolution of 60 microns for a 50 MHz transducer. Both transverse and longitudinal TSI images compare well with the B-Scan of arterial wall structures, including intima, media, adventitia and overlying fatty tissue. These in-vitro results demonstrate the feasibility of high resolution TSI with a small temperature change (less than a 1°C) for plaque characterization.

Original languageEnglish (US)
Title of host publication2005 IEEE Ultrasonics Symposium
Number of pages4
StatePublished - 2005
Event2005 IEEE Ultrasonics Symposium - Rotterdam, Netherlands
Duration: Sep 18 2005Sep 21 2005

Publication series

NameProceedings - IEEE Ultrasonics Symposium
ISSN (Print)1051-0117


Other2005 IEEE Ultrasonics Symposium

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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