Archaic admixture in the human genome

Jeffrey D. Wall, Michael F. Hammer

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

One of the enduring questions in the evolution of our species surrounds the fate of 'archaic' forms of Homo. Did Neanderthals go extinct without interbreeding with modern humans 25-40 thousand years ago or are their genes present among modern-day Europeans? Recent work suggests that Neanderthals and an as yet unidentified archaic African population contributed to at least 5% of the modern European and West African gene pools, respectively. Extensive sequencing of Neanderthal and other archaic human nuclear DNA has the potential to answer this question definitively within the next few years.

Original languageEnglish (US)
Pages (from-to)606-610
Number of pages5
JournalCurrent Opinion in Genetics and Development
Volume16
Issue number6
DOIs
StatePublished - Dec 2006

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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