Abstract
The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid- like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.
Original language | English (US) |
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Pages (from-to) | 948-950 |
Number of pages | 3 |
Journal | Science |
Volume | 273 |
Issue number | 5277 |
DOIs | |
State | Published - Aug 16 1996 |
ASJC Scopus subject areas
- General