Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism

Malcolm J. Bennett, Alan Marchant, Haydn G. Green, Sean T. May, Sally P. Ward, Paul A. Millner, Amanda R. Walker, Burkhard Schulz, Kenneth A. Feldmann

Research output: Contribution to journalArticlepeer-review

784 Scopus citations


The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid- like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.

Original languageEnglish (US)
Pages (from-to)948-950
Number of pages3
Issue number5277
StatePublished - Aug 16 1996

ASJC Scopus subject areas

  • General


Dive into the research topics of 'Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism'. Together they form a unique fingerprint.

Cite this