A patient presented with symptomatic aortic root enlargement 5 years after combined heart and double-lung transplantation for cystic fibrosis, requiring homograft aortic root replacement. Histologic examination of the resected aneurysm showed cystic medial degeneration with no evidence of infectious or atherosclerotic process. Surgical options and potential role of immunosuppressive therapy after homograft implantation are discussed.
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine