Abstract
A new lactam has been isolated from Jatropha macrorhiza (Euphorbiaceae) and has shown tumor‐inhibitory properties against the P‐388 lymphocytic leukemia test system. The compound was identified by means of NMR, UV, IR, rotary dispersion, mass spectrometry, and classical chemical procedures. It has the structure 5‐hydroxy‐4‐methyl‐3‐pyrrolin‐2‐one and has been named jatropham.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1206-1207 |
| Number of pages | 2 |
| Journal | Journal of pharmaceutical sciences |
| Volume | 62 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1973 |
Keywords
- 5‐Hydroxy‐4‐methyl‐3‐pyrrolin‐2‐one (jatropham)—isolation from Jatropha macrorhiza, characterization, antitumor activity
- Antitumor agents—isolation and characterization of jatropham (5‐hydroxy‐4‐methyl‐3‐pyrrolin‐2‐one) from Jatropha macrorhiza
- Jatropha macrorhiza (Euphorbiaceae)—isolation and characterization of jatropham (5‐hydroxy‐4‐methyl‐3‐pyrrolin‐2‐one), antitumor activity
ASJC Scopus subject areas
- Pharmaceutical Science