Antitumor agents from Bursera microphylla (Burseraceae) I. Isolation and characterization of deoxypodophyllotoxin

E. Bianchi; M. E. Caldwell; J. R. Cole

doi:10.1002/jps.2600570436

Antitumor agents from Bursera microphylla (Burseraceae) I. Isolation and characterization of deoxypodophyllotoxin

E. Bianchi, M. E. Caldwell, J. R. Cole

Pharmacy Practice and Science

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Deoxypodophyllotoxin has been isolated and characterized as one of several anti‐tumor agents from Bursera microphylla (Burseraceae). β‐Sitosterol has also been shown to be present in this plant.

Original language	English (US)
Pages (from-to)	696-697
Number of pages	2
Journal	Journal of pharmaceutical sciences
Volume	57
Issue number	4
DOIs	https://doi.org/10.1002/jps.2600570436
State	Published - Apr 1968

Keywords

Antitumor agents—Bursera microphylla
Chromatography, adsorption, thick layer, paper—separation
Deoxypodophyllotoxin—isolation, characterization
IR spectrophotometry—identity
Mass spectroscopy—identity
TLC—identity
Tumor inhibition, ED—deoxypodophyllotoxin

ASJC Scopus subject areas

Pharmaceutical Science

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title = "Antitumor agents from Bursera microphylla (Burseraceae) I. Isolation and characterization of deoxypodophyllotoxin",

abstract = "Deoxypodophyllotoxin has been isolated and characterized as one of several anti‐tumor agents from Bursera microphylla (Burseraceae). β‐Sitosterol has also been shown to be present in this plant.",

keywords = "Antitumor agents—Bursera microphylla, Chromatography, adsorption, thick layer, paper—separation, Deoxypodophyllotoxin—isolation, characterization, IR spectrophotometry—identity, Mass spectroscopy—identity, TLC—identity, Tumor inhibition, ED—deoxypodophyllotoxin",

author = "E. Bianchi and Caldwell, {M. E.} and Cole, {J. R.}",

note = "Funding Information: This investigation was supported in part by contract PH 43-63-1136, Cancer Chemotherapy National Service Center, National Cancer Institute, National Institutes of Health, and research grant CA 05076-MCHB, National Cancer Institute, U. S. Public Health Service, Bethesda, Md.",

year = "1968",

month = apr,

doi = "10.1002/jps.2600570436",

language = "English (US)",

volume = "57",

pages = "696--697",

journal = "Journal of pharmaceutical sciences",

issn = "0022-3549",

publisher = "Elsevier B.V.",

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T1 - Antitumor agents from Bursera microphylla (Burseraceae) I. Isolation and characterization of deoxypodophyllotoxin

AU - Bianchi, E.

AU - Caldwell, M. E.

AU - Cole, J. R.

N1 - Funding Information: This investigation was supported in part by contract PH 43-63-1136, Cancer Chemotherapy National Service Center, National Cancer Institute, National Institutes of Health, and research grant CA 05076-MCHB, National Cancer Institute, U. S. Public Health Service, Bethesda, Md.

PY - 1968/4

Y1 - 1968/4

N2 - Deoxypodophyllotoxin has been isolated and characterized as one of several anti‐tumor agents from Bursera microphylla (Burseraceae). β‐Sitosterol has also been shown to be present in this plant.

AB - Deoxypodophyllotoxin has been isolated and characterized as one of several anti‐tumor agents from Bursera microphylla (Burseraceae). β‐Sitosterol has also been shown to be present in this plant.

KW - Antitumor agents—Bursera microphylla

KW - Chromatography, adsorption, thick layer, paper—separation

KW - Deoxypodophyllotoxin—isolation, characterization

KW - IR spectrophotometry—identity

KW - Mass spectroscopy—identity

KW - TLC—identity

KW - Tumor inhibition, ED—deoxypodophyllotoxin

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VL - 57

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JO - Journal of pharmaceutical sciences

JF - Journal of pharmaceutical sciences

IS - 4

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Antitumor agents from Bursera microphylla (Burseraceae) I. Isolation and characterization of deoxypodophyllotoxin

Abstract

Keywords

ASJC Scopus subject areas

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