Antioxidants and AIDS

Zhen Zhang, Paula Inserra, Bailin Liang, Ronald R. Watson

Research output: Chapter in Book/Report/Conference proceedingChapter


Acquired immunodeficiency syndrome (AIDS) is a result of infection with human immunodeficiency virus (HIV-1 or HIV-2) which eventually destroys subset CD4+ helper T lymphocytes. This results in enhanced susceptibility to opportunistic infection and neoplasms. Oxidative stress plays a major role in the progression of HIV infection to AIDS and has been suggested to contribute to the decline in CD4+ lymphocytes. The existence of oxidative stress in HIV infection and AIDS is exemplified by the excess production of reactive oxygen species (ROS) and a general loss of antioxidant defenses in HIV-infected patients. Therefore, the reduction of oxidative stress by antioxidant treatment may be a desirable therapy during the asymptotic HIV infection as well as advanced AIDS.

Original languageEnglish (US)
Title of host publicationNutrients and Foods in Aids
PublisherCRC Press
Number of pages14
ISBN (Electronic)9781351427432
ISBN (Print)084938561X, 9780849385612
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • General Medicine


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