TY - JOUR
T1 - Antibody Response Following Measles-Mumps-Rubella Vaccine Under Conditions of Customary Use
AU - Brunell, Philip A.
AU - Weigle, Kristen
AU - Murphy, M. Dianne
AU - Shehab, Ziad
AU - Cobb, Elaine
PY - 1983/9/16
Y1 - 1983/9/16
N2 - A study of 301 children who had been immunized two to 19 months previously with measles, mumps, and rubella (MMR) vaccine at 36 different sites in San Antonio, Tex, including physicians' offices and clinics, revealed that 99.7% had antibody against rubella and 98.3% had antibody against measles and mumps. None of the 49 infants who were tested prior to receipt of MMR vaccine had antibody against any of these viruses, indicating that the antibody found after immunization was unlikely to be due to false-positive results. The lack of antibody in these infants confirmed that there had not been a significant number of cases of these diseases that could contribute to the high frequency of antibody found after immunization. A single dose of MMR vaccine administered under customary conditions appears to be an effective method of conferring immunity against these diseases.
AB - A study of 301 children who had been immunized two to 19 months previously with measles, mumps, and rubella (MMR) vaccine at 36 different sites in San Antonio, Tex, including physicians' offices and clinics, revealed that 99.7% had antibody against rubella and 98.3% had antibody against measles and mumps. None of the 49 infants who were tested prior to receipt of MMR vaccine had antibody against any of these viruses, indicating that the antibody found after immunization was unlikely to be due to false-positive results. The lack of antibody in these infants confirmed that there had not been a significant number of cases of these diseases that could contribute to the high frequency of antibody found after immunization. A single dose of MMR vaccine administered under customary conditions appears to be an effective method of conferring immunity against these diseases.
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U2 - 10.1001/jama.1983.03340110023025
DO - 10.1001/jama.1983.03340110023025
M3 - Article
C2 - 6887461
AN - SCOPUS:84944285452
SN - 0002-9955
VL - 250
SP - 1409
EP - 1412
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
IS - 11
ER -