Anti-Müllerian Hormone Levels among Female Firefighters

Samantha Davidson, Sara Jahnke, Alesia M. Jung, Jefferey L. Burgess, Elizabeth T. Jacobs, Dean Billheimer, Leslie V. Farland

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Female firefighters have occupational exposures which may negatively impact their reproductive health. Anti-müllerian hormone (AMH) is a clinical marker of ovarian reserve. We investigated whether AMH levels differed in female firefighters compared to non-firefighters and whether there was a dose-dependent relationship between years of firefighting and AMH levels. Female firefighters from a pre-existing cohort completed a cross-sectional survey regarding their occupational and health history and were asked to recruit a non-firefighter friend or relative. All participants provided a dried blood spot (DBS) for AMH analysis. Linear regression was used to assess the relationship between firefighting status and AMH levels. Among firefighters, the influence of firefighting-related exposures was evaluated. Firefighters (n = 106) and non-firefighters (n = 58) had similar age and BMI. Firefighters had a lower mean AMH compared to non-firefighters (2.93 ng/mL vs. 4.37 ng/mL). In multivariable adjusted models, firefighters had a 33% lower AMH value than non-firefighters (−33.38%∆ (95% CI: −54.97, −1.43)). Years of firefighting was not associated with a decrease in AMH. Firefighters in this study had lower AMH levels than non-firefighters. More research is needed to understand the mechanisms by which firefighting could reduce AMH and affect fertility.

Original languageEnglish (US)
Article number5981
JournalInternational journal of environmental research and public health
Issue number10
StatePublished - May 1 2022


  • anti-müllerian hormone
  • firefighter health
  • occupational exposures
  • reproductive health

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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