Angina induced by 5-fluorouracil infusion in a patient with normal coronaries

Reza Tajik; Habib Saadat; Maryam Taherkhani; Mohammad Reza Movahed

doi:10.15420/ahhj.2010.8.2.111

Angina induced by 5-fluorouracil infusion in a patient with normal coronaries

Reza Tajik, Habib Saadat, Maryam Taherkhani, Mohammad Reza Movahed

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

This article reviews the occurrence of angina in patients treated with 5-fluorouracil (5-FU) without significant coronary artery disease. We present a case followed by a review of the literature. A 43-year-old man with a history of colon cancer developed typical angina during intravenous infusion of 5-FU. His electrocardiogram (ECG) showed tall T waves during his angina episode. His angina and ECG changes reoccurred during a second 5-FU infusion. His coronary angiography was normal. This case is consistent with a rare occurrence of 5-FU-induced angina despite normal coronaries. Physician should be aware of this important side effect of 5-FU infusion.

Original language	English (US)
Pages (from-to)	111-112
Number of pages	2
Journal	American Heart Hospital Journal
Volume	8
Issue number	2
DOIs	https://doi.org/10.15420/ahhj.2010.8.2.111
State	Published - Dec 1 2010
Externally published	Yes

ASJC Scopus subject areas

Leadership and Management
Health Policy
Cardiology and Cardiovascular Medicine

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10.15420/ahhj.2010.8.2.111

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abstract = "This article reviews the occurrence of angina in patients treated with 5-fluorouracil (5-FU) without significant coronary artery disease. We present a case followed by a review of the literature. A 43-year-old man with a history of colon cancer developed typical angina during intravenous infusion of 5-FU. His electrocardiogram (ECG) showed tall T waves during his angina episode. His angina and ECG changes reoccurred during a second 5-FU infusion. His coronary angiography was normal. This case is consistent with a rare occurrence of 5-FU-induced angina despite normal coronaries. Physician should be aware of this important side effect of 5-FU infusion.",

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AB - This article reviews the occurrence of angina in patients treated with 5-fluorouracil (5-FU) without significant coronary artery disease. We present a case followed by a review of the literature. A 43-year-old man with a history of colon cancer developed typical angina during intravenous infusion of 5-FU. His electrocardiogram (ECG) showed tall T waves during his angina episode. His angina and ECG changes reoccurred during a second 5-FU infusion. His coronary angiography was normal. This case is consistent with a rare occurrence of 5-FU-induced angina despite normal coronaries. Physician should be aware of this important side effect of 5-FU infusion.

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Angina induced by 5-fluorouracil infusion in a patient with normal coronaries

Abstract

ASJC Scopus subject areas

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