Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Kevin A. Scott, Jon T. Njardarson

Research output: Contribution to journalReview articlepeer-review

501 Scopus citations


In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

Original languageEnglish (US)
Article number5
JournalTopics in Current Chemistry
Issue number1
StatePublished - Feb 1 2018


  • Sulfate
  • Sulfonamide
  • Sulfone
  • Sulfoxide
  • Sulfur heterocycle
  • Thioether

ASJC Scopus subject areas

  • Chemistry(all)


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