Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Kevin A. Scott; Jon T. Njardarson

doi:10.1007/s41061-018-0184-5

Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Kevin A. Scott, Jon T. Njardarson

Research output: Contribution to journal › Review article › peer-review

647 Scopus citations

Abstract

In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

Original language	English (US)
Article number	5
Journal	Topics in Current Chemistry
Volume	376
Issue number	1
DOIs	https://doi.org/10.1007/s41061-018-0184-5
State	Published - Feb 1 2018
Externally published	Yes

Keywords

Sulfate
Sulfonamide
Sulfone
Sulfoxide
Sulfur heterocycle
Thioether

ASJC Scopus subject areas

General Chemistry

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10.1007/s41061-018-0184-5

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title = "Analysis of US FDA-Approved Drugs Containing Sulfur Atoms",

abstract = "In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.",

keywords = "Sulfate, Sulfonamide, Sulfone, Sulfoxide, Sulfur heterocycle, Thioether",

author = "Scott, {Kevin A.} and Njardarson, {Jon T.}",

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AU - Njardarson, Jon T.

N1 - Funding Information: The funding was provided by National Science Foundation (Grant no. CHE-1565500). Funding Information: Acknowledgements The funding was provided by National Science Foundation (Grant no. CHE-1565500). Publisher Copyright: © 2018, Springer International Publishing AG, part of Springer Nature.

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N2 - In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

AB - In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

KW - Sulfate

KW - Sulfonamide

KW - Sulfone

KW - Sulfoxide

KW - Sulfur heterocycle

KW - Thioether

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Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Abstract

Keywords

ASJC Scopus subject areas

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