Analysis of survivors more than 10 years after heart transplantation in the cyclosporine era: Stanford experience

Nobuyuki Shiba, Michael C.Y. Chan, Bernard W.K. Kwok, Hannah A. Valantine, Robert C. Robbins, Sharon A. Hunt

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Background: Truly long term survival post heart transplantation has become increasingly frequent over the past two decades. Methods: We analyzed multiple clinical outcomes in the cohort of 140 patients in the Stanford database who underwent heart transplantation after the introduction of cyclosporine-based immunosuppression in 1980 and survived >10 years after transplantation. Results: We found generally excellent functional status in these patients, but a high incidence of hypertension, renal dysfunction, and graft CAD as well as malignancy. Conclusion: With continued improvement in post-transplant survival rates, providing complex care for such long-term recipients as these will assume increasing clinical importance in the everyday practice of transplant medicine and these data highlight the problems to be anticipated.

Original languageEnglish (US)
Pages (from-to)155-164
Number of pages10
JournalJournal of Heart and Lung Transplantation
Volume23
Issue number2
DOIs
StatePublished - Feb 2004
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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