Analysis of oxygen exchange between arterioles and surrounding capillary-perfused tissue

R. Hsu, T. W. Secomb

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A theoretical model is used to analyze oxygen transport in a three-dimensional tissue region containing an arteriole surrounded by an array of capillaries in planes perpendicular to the arteriole. Convective removal of oxygen from the vicinity of the arteriole by nearby capillaries is shown to increase diffusive oxygen loss from the arteriole. This effect depends on the locations of the capillaries, particularly those nearest to the arteriole. The arteriolar oxygen efflux is comparable to that predicted by a previous model which used a continuum approach, but the efflux does not increase with increasing perfusion as rapidly as predicted by the continuum model. Even a small capillary flow rate strongly influences the oxygen field surrounding the arteriole.

Original languageEnglish (US)
Pages (from-to)227-231
Number of pages5
JournalJournal of Biomechanical Engineering
Issue number2
StatePublished - May 1992

ASJC Scopus subject areas

  • Biomedical Engineering
  • Physiology (medical)


Dive into the research topics of 'Analysis of oxygen exchange between arterioles and surrounding capillary-perfused tissue'. Together they form a unique fingerprint.

Cite this