TY - GEN
T1 - Analysis of Adaptive Multi-Pinhole Aperture Plates for Brain SPECT Imaging
AU - May, Micaehla
AU - Ruiz-Gonzalez, Maria
AU - Richards, R. Garrett
AU - King, Michael A.
AU - Kupinski, Matthew A.
AU - Kuo, Phillip K.
AU - Furenlid, Lars R.
N1 - Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - We are developing AdaptiSPECT-C, a dynamic multiple pinhole, single-photon emission computed tomography (SPECT) system dedicated to whole brain imaging whose primary purpose is to acquire data for pharmacokinetic analysis. We have designed prototype hardware, control electronics and software that create adjustable pinhole apertures for this clinical SPECT system. The design enables us to dynamically move between imaging configurations corresponding to a variety of desired resolutions and sensitivities. Preliminary testing is necessary to evaluate the aperture assembly performance and reliability. Modular aperture plates are designed to provide multiple choices for the trade-offs between resolution and sensitivity, in order to improve pharmacokinetic SPECT imaging. Each camera is outfitted with 5 adaptive pinholes that can be adjusted to different diameters. These apertures are designed to respond to evolving biodistributions of radiotracers. We present the results of testing the operation of the aperture plate system. We captured projections from a variety pinhole imaging configurations with a point source object.
AB - We are developing AdaptiSPECT-C, a dynamic multiple pinhole, single-photon emission computed tomography (SPECT) system dedicated to whole brain imaging whose primary purpose is to acquire data for pharmacokinetic analysis. We have designed prototype hardware, control electronics and software that create adjustable pinhole apertures for this clinical SPECT system. The design enables us to dynamically move between imaging configurations corresponding to a variety of desired resolutions and sensitivities. Preliminary testing is necessary to evaluate the aperture assembly performance and reliability. Modular aperture plates are designed to provide multiple choices for the trade-offs between resolution and sensitivity, in order to improve pharmacokinetic SPECT imaging. Each camera is outfitted with 5 adaptive pinholes that can be adjusted to different diameters. These apertures are designed to respond to evolving biodistributions of radiotracers. We present the results of testing the operation of the aperture plate system. We captured projections from a variety pinhole imaging configurations with a point source object.
UR - http://www.scopus.com/inward/record.url?scp=85185377385&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85185377385&partnerID=8YFLogxK
U2 - 10.1109/NSS/MIC44845.2022.10399078
DO - 10.1109/NSS/MIC44845.2022.10399078
M3 - Conference contribution
AN - SCOPUS:85185377385
T3 - 2022 IEEE NSS/MIC RTSD - IEEE Nuclear Science Symposium, Medical Imaging Conference and Room Temperature Semiconductor Detector Conference
BT - 2022 IEEE NSS/MIC RTSD - IEEE Nuclear Science Symposium, Medical Imaging Conference and Room Temperature Semiconductor Detector Conference
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2022 IEEE Nuclear Science Symposium, Medical Imaging Conference, and Room Temperature Semiconductor Detector Conference, IEEE NSS MIC RTSD 2022
Y2 - 5 November 2022 through 12 November 2022
ER -