Analogs of oxytocin containing a modified peptide bond

MICHAL LEBL; ELIZABETH E. SUGG; GEORGES VAN BINST; PIERRE VANDER ELST; DIRK TOURWÉ; JIŘINA SLANINOVÁ; VICTOR J. HRUBY

doi:10.1111/j.1399-3011.1987.tb03337.x

Analogs of oxytocin containing a modified peptide bond

MICHAL LEBL, ELIZABETH E. SUGG, GEORGES VAN BINST, PIERRE VANDER ELST, DIRK TOURWÉ, JIŘINA SLANINOVÁ, VICTOR J. HRUBY

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Analogs of deamino‐oxytocin and deamino‐oxypressin containing a CH₂‐NH group instead of an amide bond between positions 8 and 9 were synthesized. All tested compounds exhibit significantly lowered biological activities.

Original language	English (US)
Pages (from-to)	318-322
Number of pages	5
Journal	International journal of peptide and protein research
Volume	30
Issue number	3
DOIs	https://doi.org/10.1111/j.1399-3011.1987.tb03337.x
State	Published - Sep 1987

Keywords

modified peptide bonds
oxypressin analogs
oxytocin analogs

ASJC Scopus subject areas

Biochemistry

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10.1111/j.1399-3011.1987.tb03337.x

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title = "Analogs of oxytocin containing a modified peptide bond",

abstract = "Analogs of deamino‐oxytocin and deamino‐oxypressin containing a CH2‐NH group instead of an amide bond between positions 8 and 9 were synthesized. All tested compounds exhibit significantly lowered biological activities.",

keywords = "modified peptide bonds, oxypressin analogs, oxytocin analogs",

author = "MICHAL LEBL and SUGG, \{ELIZABETH E.\} and \{VAN BINST\}, GEORGES and ELST, \{PIERRE VANDER\} and DIRK TOURW{\'E} and JI{\v R}INA SLANINOV{\'A} and HRUBY, \{VICTOR J.\}",

year = "1987",

month = sep,

doi = "10.1111/j.1399-3011.1987.tb03337.x",

language = "English (US)",

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journal = "International journal of peptide and protein research",

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T1 - Analogs of oxytocin containing a modified peptide bond

AU - LEBL, MICHAL

AU - SUGG, ELIZABETH E.

AU - VAN BINST, GEORGES

AU - ELST, PIERRE VANDER

AU - TOURWÉ, DIRK

AU - SLANINOVÁ, JIŘINA

AU - HRUBY, VICTOR J.

PY - 1987/9

Y1 - 1987/9

N2 - Analogs of deamino‐oxytocin and deamino‐oxypressin containing a CH2‐NH group instead of an amide bond between positions 8 and 9 were synthesized. All tested compounds exhibit significantly lowered biological activities.

AB - Analogs of deamino‐oxytocin and deamino‐oxypressin containing a CH2‐NH group instead of an amide bond between positions 8 and 9 were synthesized. All tested compounds exhibit significantly lowered biological activities.

KW - modified peptide bonds

KW - oxypressin analogs

KW - oxytocin analogs

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U2 - 10.1111/j.1399-3011.1987.tb03337.x

DO - 10.1111/j.1399-3011.1987.tb03337.x

M3 - Article

C2 - 3692679

AN - SCOPUS:0023278323

SN - 0367-8377

VL - 30

SP - 318

EP - 322

JO - International journal of peptide and protein research

JF - International journal of peptide and protein research

IS - 3

ER -

Analogs of oxytocin containing a modified peptide bond

Abstract

Keywords

ASJC Scopus subject areas

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