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Analogs of oxytocin containing a modified peptide bond

  • MICHAL LEBL
  • , ELIZABETH E. SUGG
  • , GEORGES VAN BINST
  • , PIERRE VANDER ELST
  • , DIRK TOURWÉ
  • , JIŘINA SLANINOVÁ
  • , VICTOR J. HRUBY

Research output: Contribution to journalArticlepeer-review

Abstract

Analogs of deamino‐oxytocin and deamino‐oxypressin containing a CH2‐NH group instead of an amide bond between positions 8 and 9 were synthesized. All tested compounds exhibit significantly lowered biological activities.

Original languageEnglish (US)
Pages (from-to)318-322
Number of pages5
JournalInternational journal of peptide and protein research
Volume30
Issue number3
DOIs
StatePublished - Sep 1987
Externally publishedYes

Keywords

  • modified peptide bonds
  • oxypressin analogs
  • oxytocin analogs

ASJC Scopus subject areas

  • Biochemistry

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