TY - JOUR
T1 - An overview on field-flow fractionation techniques and their applications in the separation and characterization of polymers
AU - Messaud, Fathi A.
AU - Sanderson, Ron D.
AU - Runyon, J. Ray
AU - Otte, Tino
AU - Pasch, Harald
AU - Williams, S. Kim Ratanathanawongs
N1 - Funding Information:
JRR and SKRW gratefully acknowledge support from the National Science Foundation (CHE-0515521). RDS, FAM and HP wish to thank the Macromolecular Institute in Libya for support and M Hurndal for help in preparation.
PY - 2009/4
Y1 - 2009/4
N2 - Field-flow fractionation (FFF) is a family of analytical techniques developed specifically for separating and characterizing macromolecules, supramolecular assemblies, colloids and particles. It combines the effects of a laminar flow profile with an exponential concentration profile of analyte components caused by their interactions with a physical field applied perpendicular to the flow of a carrier liquid. FFF is undergoing increasingly widespread use as researchers learn of its potential and versatility. This overview underlines the basic principle and theory behind FFF and reviews recent research efforts incorporating flow and thermal FFF methods to characterize natural, biological, and synthetic polymers. These FFF techniques will be discussed in terms of theory and practice. Selected applications of FFF and their coupling capability with other chromatographic techniques or spectrometric detection for the separation and characterization of polymers in organic and aqueous media are presented.
AB - Field-flow fractionation (FFF) is a family of analytical techniques developed specifically for separating and characterizing macromolecules, supramolecular assemblies, colloids and particles. It combines the effects of a laminar flow profile with an exponential concentration profile of analyte components caused by their interactions with a physical field applied perpendicular to the flow of a carrier liquid. FFF is undergoing increasingly widespread use as researchers learn of its potential and versatility. This overview underlines the basic principle and theory behind FFF and reviews recent research efforts incorporating flow and thermal FFF methods to characterize natural, biological, and synthetic polymers. These FFF techniques will be discussed in terms of theory and practice. Selected applications of FFF and their coupling capability with other chromatographic techniques or spectrometric detection for the separation and characterization of polymers in organic and aqueous media are presented.
KW - Copolymer composition
KW - Diffusion coefficient
KW - Field-flow fractionation
KW - High temperature separation
KW - Size exclusion chromatography
KW - Thermal diffusion coefficient
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U2 - 10.1016/j.progpolymsci.2008.11.001
DO - 10.1016/j.progpolymsci.2008.11.001
M3 - Review article
AN - SCOPUS:63149152658
SN - 0079-6700
VL - 34
SP - 351
EP - 368
JO - Progress in Polymer Science
JF - Progress in Polymer Science
IS - 4
ER -