An expeditious approach toward the total synthesis of CP-263,114

Jón T. Njardarson, Ivar M. McDonald, David A. Spiegel, Munenori Inoue, John L. Wood

Research output: Contribution to journalArticlepeer-review

56 Scopus citations


matrix presented Assembly of the carbocyclic core of CP-263,114 has been accomplished efficiently and in high yield. Key steps include a phenolic oxidation/ intramolecular Diels-Alder sequence, tandem radical cyclization, and the late-stage fragmentation of a densely functionalized isotwistane skeleton.

Original languageEnglish (US)
Pages (from-to)2435-2438
Number of pages4
JournalOrganic Letters
Issue number16
StatePublished - Aug 9 2001

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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