Abstract
An expeditious cascade protocol for the synthesis of functionalized imidazo[1,2-a]pyridin-3-ols was developed based on the Petasis reaction. With the availability of commercial reagents and high efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of imidazo-pyridin-3-ol analogues.
Original language | English (US) |
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Pages (from-to) | 1281-1284 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 55 |
Issue number | 7 |
DOIs | |
State | Published - Feb 12 2014 |
Externally published | Yes |
Keywords
- 2-Arylimidazo[1,2-a]pyridine-3-ol
- Cascade reaction
- MCR
- Petasis reaction
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry