An estimate of the global error frequency in translation

Nathan Ellis, Jonathan Gallant

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Electrophoretic heterogeneity in a set of selected proteins is used to estimate the average error frequency during translation. Estimates based upon streptomycin-induced heterogeneity as well as mistranslation of an ochre codon yield an average error frequency of 4x10-4 for normally growing cells.

Original languageEnglish (US)
Pages (from-to)169-172
Number of pages4
JournalMGG Molecular & General Genetics
Volume188
Issue number2
DOIs
StatePublished - Dec 1982

ASJC Scopus subject areas

  • Genetics

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