TY - JOUR
T1 - An economic evaluation of coordinated specialty care (CSC) services for first-episode psychosis in the U.S. public sector
AU - Murphy, Sean M.
AU - Kucukgoncu, Suat
AU - Bao, Yuhua
AU - Li, Fangyong
AU - Tek, Cenk
AU - Breitborde, Nicholas J.K.
AU - Guloksuz, Sinan
AU - Phutane, Vivek H.
AU - Ozkan, Banu
AU - Pollard, Jessica M.
AU - Cahill, John D.
AU - Woods, Scott W.
AU - Cole, Robert A.
AU - Schoenbaum, Michael
AU - Srihari, Vinod H.
N1 - Funding Information:
* Correspondence to: Sean M. Murphy, Ph.D., Department of Healthcare Policy & Research, 425 East 61st Street, Suite 301, New York, NY 10065, USA. Tel.: +1-646-962 9710 E-mail: [email protected] Source of Funding: This work was supported by grants to Dr. Srihari, principal investigator, from the Patrick and Catherine Weldon Donaghue Medical Research Foundation (DF07-014) and the National Institutes of Health (MH088971). The trial is registered at ClinicalTrials.gov (NCT00309452). The views expressed here are those of the authors, and not necessarily those of the National Institute of Mental Health, the National Institutes of Health, or the federal government. This work was funded in part by the State of Connecticut, Department of Mental Health and Addiction Services, but this publication does not express the views of the Department of Mental Health and Addiction Services or the State of Connecticut. The views and opinions expressed are those of the authors.
Publisher Copyright:
Copyright © 2018 ICMPE
PY - 2018
Y1 - 2018
N2 - Background: Schizophrenia spectrum disorders exert a large and disproportionate economic impact. Early intervention services may be able to alleviate the burden of schizophrenia spectrum disorders on diagnosed individuals, caregivers, and society at large. Economic analyses of observational studies have supported investments in specialized team-based care for early psychosis; however, questions remain regarding the economic viability of first-episode services in the fragmented U.S. healthcare system. The clinic for Specialized Treatment Early in Psychosis (STEP) was established in 2006, to explicitly model a nationally-relevant U.S. public-sector early intervention service. The purpose of this study was to conduct an economic evaluation of STEP, a Coordinated Specialty Care service (CSC) based in a U.S. State-funded community mental health center, relative to usual treatment (UT). Methods: Eligible patients were within 5 years of psychosis onset and had no more than 12 weeks of lifetime antipsychotic exposure. Participants were randomized to STEP or UT. The annual per-patient cost of the STEP intervention per se was estimated assuming a steady-state caseload of 30 patients. A cost-offset analysis was conducted to estimate the net value of STEP from a third-party payer perspective. Participant healthcare service utilization was evaluated at 6 months and over the entire 12 months post randomization. Generalized linear model multivariable regressions were used to estimate the effect of STEP on healthcare costs over time, and generate predicted mean costs, which were combined with the per-patient cost of STEP. Results: The annual per-patient cost of STEP was $1,984. STEP participants were significantly less likely to have any inpatient or ED visits; among individuals who did use such services in a given period, the associated costs were significantly lower for STEP participants at month 12. We did not observe a similar effect with regard to other healthcare services. The predicted average total costs were lower for STEP than UT, indicating a net benefit for STEP of $1,029 at month 6 and $2,991 at month 12; however, the differences were not statistically significant. Conclusions: Our findings are promising with regard to the value of STEP to third-party payers.
AB - Background: Schizophrenia spectrum disorders exert a large and disproportionate economic impact. Early intervention services may be able to alleviate the burden of schizophrenia spectrum disorders on diagnosed individuals, caregivers, and society at large. Economic analyses of observational studies have supported investments in specialized team-based care for early psychosis; however, questions remain regarding the economic viability of first-episode services in the fragmented U.S. healthcare system. The clinic for Specialized Treatment Early in Psychosis (STEP) was established in 2006, to explicitly model a nationally-relevant U.S. public-sector early intervention service. The purpose of this study was to conduct an economic evaluation of STEP, a Coordinated Specialty Care service (CSC) based in a U.S. State-funded community mental health center, relative to usual treatment (UT). Methods: Eligible patients were within 5 years of psychosis onset and had no more than 12 weeks of lifetime antipsychotic exposure. Participants were randomized to STEP or UT. The annual per-patient cost of the STEP intervention per se was estimated assuming a steady-state caseload of 30 patients. A cost-offset analysis was conducted to estimate the net value of STEP from a third-party payer perspective. Participant healthcare service utilization was evaluated at 6 months and over the entire 12 months post randomization. Generalized linear model multivariable regressions were used to estimate the effect of STEP on healthcare costs over time, and generate predicted mean costs, which were combined with the per-patient cost of STEP. Results: The annual per-patient cost of STEP was $1,984. STEP participants were significantly less likely to have any inpatient or ED visits; among individuals who did use such services in a given period, the associated costs were significantly lower for STEP participants at month 12. We did not observe a similar effect with regard to other healthcare services. The predicted average total costs were lower for STEP than UT, indicating a net benefit for STEP of $1,029 at month 6 and $2,991 at month 12; however, the differences were not statistically significant. Conclusions: Our findings are promising with regard to the value of STEP to third-party payers.
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M3 - Article
C2 - 30530872
AN - SCOPUS:85052705411
SN - 1091-4358
VL - 21
SP - 123
EP - 130
JO - Journal of Mental Health Policy and Economics
JF - Journal of Mental Health Policy and Economics
IS - 3
ER -