An analysis of 45ca fluxes in the rabbit Lens

C. A. Paterson; N. A. Delamere

doi:10.3109/02713688209020004

An analysis of ⁴⁵ca fluxes in the rabbit Lens

C. A. Paterson, N. A. Delamere

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The uptake of ⁴⁵Ca by the rabbit lens reached equilibrium within 20 hr; the steady state lens/medium ratio was 0.08. This ratio is similar to that found for the lens/medium distribution of extracellular markers. Efflux of ⁴⁵Ca from the lens was rapid and insensitive to iodoacetate. Mathematical analysis of ⁴⁵Ca efflux curves revealed that calcium efflux from the lens could be described solely upon the basis of passive movement from the extracellular space. It is concluded that the exchangeable calcium in the normal rabbit lens is predominantly located in the extracellular space.

Original language	English (US)
Pages (from-to)	727-734
Number of pages	8
Journal	Current Eye Research
Volume	2
Issue number	11
DOIs	https://doi.org/10.3109/02713688209020004
State	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

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title = "An analysis of 45ca fluxes in the rabbit Lens",

abstract = "The uptake of 45Ca by the rabbit lens reached equilibrium within 20 hr; the steady state lens/medium ratio was 0.08. This ratio is similar to that found for the lens/medium distribution of extracellular markers. Efflux of 45Ca from the lens was rapid and insensitive to iodoacetate. Mathematical analysis of 45Ca efflux curves revealed that calcium efflux from the lens could be described solely upon the basis of passive movement from the extracellular space. It is concluded that the exchangeable calcium in the normal rabbit lens is predominantly located in the extracellular space.",

author = "Paterson, {C. A.} and Delamere, {N. A.}",

note = "Funding Information: ACKNOWLEDGEMENTS We thank Ted Cotton and Elizabeth Paterson for technical assistance. This study was supported by USPHS Research grant EY 00506 from the National Eye 1nstit.ut.e.",

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doi = "10.3109/02713688209020004",

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AU - Delamere, N. A.

N1 - Funding Information: ACKNOWLEDGEMENTS We thank Ted Cotton and Elizabeth Paterson for technical assistance. This study was supported by USPHS Research grant EY 00506 from the National Eye 1nstit.ut.e.

PY - 1982

Y1 - 1982

N2 - The uptake of 45Ca by the rabbit lens reached equilibrium within 20 hr; the steady state lens/medium ratio was 0.08. This ratio is similar to that found for the lens/medium distribution of extracellular markers. Efflux of 45Ca from the lens was rapid and insensitive to iodoacetate. Mathematical analysis of 45Ca efflux curves revealed that calcium efflux from the lens could be described solely upon the basis of passive movement from the extracellular space. It is concluded that the exchangeable calcium in the normal rabbit lens is predominantly located in the extracellular space.

AB - The uptake of 45Ca by the rabbit lens reached equilibrium within 20 hr; the steady state lens/medium ratio was 0.08. This ratio is similar to that found for the lens/medium distribution of extracellular markers. Efflux of 45Ca from the lens was rapid and insensitive to iodoacetate. Mathematical analysis of 45Ca efflux curves revealed that calcium efflux from the lens could be described solely upon the basis of passive movement from the extracellular space. It is concluded that the exchangeable calcium in the normal rabbit lens is predominantly located in the extracellular space.

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An analysis of ⁴⁵ca fluxes in the rabbit Lens

Abstract

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