An amine sulfonamide organocatalyst for promoting direct, highly enantioselective α-aminoxylation reactions of aldehydes and ketones

Wei Wang; Jian Wang; Hao Li; Lixin Liao

doi:10.1016/j.tetlet.2004.08.029

An amine sulfonamide organocatalyst for promoting direct, highly enantioselective α-aminoxylation reactions of aldehydes and ketones

Wei Wang
, Jian Wang
, Hao Li
, Lixin Liao

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Abstract

A novel, pyrrolidine sulfonamide-based organocatalyst has been developed and used to catalyze direct, efficient and α-aminoxylation reactions of aldehydes and ketones with excellent regio- and enantioselectivities. Unlike l-proline, the new catalyst exhibits high activity and enantioselectivity when used in a variety of organic solvents.

Original language	English (US)
Pages (from-to)	7235-7238
Number of pages	4
Journal	Tetrahedron Letters
Volume	45
Issue number	39
DOIs	https://doi.org/10.1016/j.tetlet.2004.08.029
State	Published - Sep 20 2004
Externally published	Yes

Keywords

Aldehydes
Asymmetric catalysis
Ketones
Pyrrolidine sulfonamide
α-Aminoxylation

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2004.08.029

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title = "An amine sulfonamide organocatalyst for promoting direct, highly enantioselective α-aminoxylation reactions of aldehydes and ketones",

abstract = "A novel, pyrrolidine sulfonamide-based organocatalyst has been developed and used to catalyze direct, efficient and α-aminoxylation reactions of aldehydes and ketones with excellent regio- and enantioselectivities. Unlike l-proline, the new catalyst exhibits high activity and enantioselectivity when used in a variety of organic solvents.",

keywords = "Aldehydes, Asymmetric catalysis, Ketones, Pyrrolidine sulfonamide, α-Aminoxylation",

author = "Wei Wang and Jian Wang and Hao Li and Lixin Liao",

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language = "English (US)",

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T1 - An amine sulfonamide organocatalyst for promoting direct, highly enantioselective α-aminoxylation reactions of aldehydes and ketones

AU - Wang, Wei

AU - Wang, Jian

AU - Li, Hao

AU - Liao, Lixin

PY - 2004/9/20

Y1 - 2004/9/20

N2 - A novel, pyrrolidine sulfonamide-based organocatalyst has been developed and used to catalyze direct, efficient and α-aminoxylation reactions of aldehydes and ketones with excellent regio- and enantioselectivities. Unlike l-proline, the new catalyst exhibits high activity and enantioselectivity when used in a variety of organic solvents.

AB - A novel, pyrrolidine sulfonamide-based organocatalyst has been developed and used to catalyze direct, efficient and α-aminoxylation reactions of aldehydes and ketones with excellent regio- and enantioselectivities. Unlike l-proline, the new catalyst exhibits high activity and enantioselectivity when used in a variety of organic solvents.

KW - Aldehydes

KW - Asymmetric catalysis

KW - Ketones

KW - Pyrrolidine sulfonamide

KW - α-Aminoxylation

UR - https://www.scopus.com/pages/publications/4444260494

UR - https://www.scopus.com/pages/publications/4444260494#tab=citedBy

U2 - 10.1016/j.tetlet.2004.08.029

DO - 10.1016/j.tetlet.2004.08.029

M3 - Article

AN - SCOPUS:4444260494

SN - 0040-4039

VL - 45

SP - 7235

EP - 7238

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 39

ER -

An amine sulfonamide organocatalyst for promoting direct, highly enantioselective α-aminoxylation reactions of aldehydes and ketones

Abstract

Keywords

ASJC Scopus subject areas

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