Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line

Yasuhiro Nakayama; Yoshiki Iwamoto; Stephen E. Maher; Yujiro Tanaka; Alfred L.M. Bothwell

doi:10.1006/bbrc.2000.3639

Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line

Yasuhiro Nakayama, Yoshiki Iwamoto, Stephen E. Maher, Yujiro Tanaka, Alfred L.M. Bothwell

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Burkitt's lymphoma cell line, BL2 was stimulated by surface BCR cross-linking and altered gene expression was analyzed by RDA methodology. Consistent with previous reports, we detected up-regulated MDC, IL6R and adhesion molecule LFA1. We also detected gene expression of SIRPα, anti-apoptotic A-20, signal regulatory SLP76 and BCAR3, DNA binding proteins EGR2 and DEC1 in addition to some new genes. (C) 2000 Academic Press.

Original language	English (US)
Pages (from-to)	124-127
Number of pages	4
Journal	Biochemical and Biophysical Research Communications
Volume	277
Issue number	1
DOIs	https://doi.org/10.1006/bbrc.2000.3639
State	Published - Oct 14 2000
Externally published	Yes

Keywords

BCR cross-linking
Burkitt's lymphoma cell
Gene expression
RDA
Transcription factors

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1006/bbrc.2000.3639

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title = "Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line",

abstract = "Burkitt's lymphoma cell line, BL2 was stimulated by surface BCR cross-linking and altered gene expression was analyzed by RDA methodology. Consistent with previous reports, we detected up-regulated MDC, IL6R and adhesion molecule LFA1. We also detected gene expression of SIRPα, anti-apoptotic A-20, signal regulatory SLP76 and BCAR3, DNA binding proteins EGR2 and DEC1 in addition to some new genes. (C) 2000 Academic Press.",

keywords = "BCR cross-linking, Burkitt's lymphoma cell, Gene expression, RDA, Transcription factors",

author = "Yasuhiro Nakayama and Yoshiki Iwamoto and Maher, {Stephen E.} and Yujiro Tanaka and Bothwell, {Alfred L.M.}",

year = "2000",

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doi = "10.1006/bbrc.2000.3639",

language = "English (US)",

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AU - Nakayama, Yasuhiro

AU - Iwamoto, Yoshiki

AU - Maher, Stephen E.

AU - Tanaka, Yujiro

AU - Bothwell, Alfred L.M.

PY - 2000/10/14

Y1 - 2000/10/14

N2 - Burkitt's lymphoma cell line, BL2 was stimulated by surface BCR cross-linking and altered gene expression was analyzed by RDA methodology. Consistent with previous reports, we detected up-regulated MDC, IL6R and adhesion molecule LFA1. We also detected gene expression of SIRPα, anti-apoptotic A-20, signal regulatory SLP76 and BCAR3, DNA binding proteins EGR2 and DEC1 in addition to some new genes. (C) 2000 Academic Press.

AB - Burkitt's lymphoma cell line, BL2 was stimulated by surface BCR cross-linking and altered gene expression was analyzed by RDA methodology. Consistent with previous reports, we detected up-regulated MDC, IL6R and adhesion molecule LFA1. We also detected gene expression of SIRPα, anti-apoptotic A-20, signal regulatory SLP76 and BCAR3, DNA binding proteins EGR2 and DEC1 in addition to some new genes. (C) 2000 Academic Press.

KW - BCR cross-linking

KW - Burkitt's lymphoma cell

KW - Gene expression

KW - RDA

KW - Transcription factors

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EP - 127

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

IS - 1

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Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line

Abstract

Keywords

ASJC Scopus subject areas

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